Table 1 The association between LH1 or SEPT2 expression and clinicopathological parameters
Features | No. of patients (%) | LH1 expression status | P | SEPT2 expression status | P | ||
|---|---|---|---|---|---|---|---|
Low (n = 92) No.patient (%) | High (n = 61) No.patient (%) | Low (n = 80) No.patient (%) | High (n = 73) No.patient (%) | ||||
Gender | |||||||
Male | 131(85.1%) | 78(59.5%) | 53(40.5%) | 0.717 | 67(51.1%) | 64(48.9%) | 0.490 |
Female | 23(14.1%) | 14(63.6%) | 8(40.5%) | Â | 13(59.1%) | 9(40.9%) | Â |
Age | |||||||
 ≤ 52 | 83(%) | 49(59.0%) | 34(41.0%) | 0.763 | 15 | 39(47.0%) | 0.845 |
 > 52 | 71(%) | 43(61.4%) | 27(38.6%) |  | 36(51.4%) | 34(48.6%) |  |
Number | |||||||
1 | 124(%) | 75(60.5%) | 49(39.5%) | 0.313 | 62(50.0%) | 62(50.0%) | 0.079 |
2 | 12(%) | 9(75.0%) | 3(25.0%) | Â | 10(83.3%) | 2(16.7%) | Â |
3 or more | 17(%) | 8(47.1%) | 9(52.9%) | Â | 8(47.1%) | 9(52.9%) | Â |
Tumor size(cm) | |||||||
 ≤ 3 | 54(%) | 35(64.8%) | 19(35.2%) | 0.382 | 28(51.9%) | 26(48.1%) | 0.936 |
 > 3 | 100(%) | 57(57.6%) | 42(42.4%) |  | 52(52.5%) | 47(47.5%) |  |
Tumor size(cm) | |||||||
 ≤ 5 | 92(%) | 57(62.0%) | 35(38.0%) | 0.571 | 45(48.9%) | 47(51.1%) | 0.305 |
 > 5 | 62(%) | 35(57.4%) | 26(42.6%) |  | 35(57.4%) | 26(42.6%) |  |
Macrovessel invasion | |||||||
No | 138(%) | 87(63.0%) | 51(37.0%) | 0.026 | 75(54.3%) | 63(45.7%) | 0.122 |
Yes | 15(%) | 5(33.3%) | 10(66.7%) | Â | 5(33.3%) | 10(66.7%) | Â |
Distant metastasis | |||||||
0 | 140(%) | 87(62.1%) | 53(37.9%) | 0.095 | 73(52.1%) | 67(47.9%) | 0.906 |
1 | 13(%) | 5(38.5%) | 8(61.5%) | Â | 7(53.8%) | 6(46.2%) | Â |
BCLC stage | |||||||
0 | 25(%) | 20(80.0%) | 5(20.0%) | 0.010 | 15(60.0%) | 10(40.0%) | 0.038 |
1 | 91(%) | 56(61.5%) | 35(38.5%) | Â | 45(49.5%) | 46(50.5%) | Â |
2 | 13(%) | 8(61.5%) | 5(38.5%) | Â | 11(84.6%) | 2(15.4%) | Â |
3 | 24(%) | 8(33.3%) | 16(66.7%) | Â | 9(37.5%) | 15(62.5%) | Â |
Differentiation degree | |||||||
Poor | 30(%) | 19(63.3%) | 11(36.7%) | 0.525 | 20(66.7%) | 10(33.3%) | 0.025 |
Moderate | 103(%) | 59(57.3%) | 44(42.7%) | Â | 46(44.7%) | 57(55.5%) | Â |
Well | 20(%) | 14(70.0%) | 6(30.0%) | Â | 14(70.0%) | 6(30.0%) | Â |
Microinvasion | |||||||
Negative | 136(%) | 84(61.8%) | 52(38.2%) | 0.243 | 75(55.1%) | 61(44.9%) | 0.045 |
Positive | 17(%) | 8(47.1%) | 9(52.9%) | Â | 5(29.4%) | 12(70.6%) | Â |
SEPT2 expression status | |||||||
low | 80(%) | 63(78.8%) | 17(21.3) | 0.000 | - | - | - |
high | 74(%) | 29(39.2%) | 45(60.8%) | Â | - | - | - |