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Fig. 3 | Molecular Cancer

Fig. 3

From: Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma

Fig. 3

CircCCAR1 promotes HCC metastasis in vitro and in vivo. A-B The migration capacity of HCC cells was evaluated by wound‐healing assays. C-D The migration and invasion abilities of HCC cells were evaluated using Transwell assays. E Gross observation of lung metastases in mice (n = 9). F The number of metastatic nodules was counted. G Lung sections were stained with H&E. *p < 0.05, **p < 0.01, ***p < 0.001 vs. vector; #p < 0.05, ##p < 0.01, ###p < 0.001 vs. sh-NC

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