Fig. 2
From: The function and mechanisms of action of circular RNAs in Urologic Cancer
Biological functions of circRNAs in kidney cancer
(A) CircRNAs are involved in the cell proliferation and cycle of kidney cancer. CircCHT15, circSCARB1, circMTO1, and circEGLN3 affect the cell proliferation of kidney cancer cells by regulating the expression of miRNAs and related proteins. (B) CircRNAs are involved in the metastasis and EMT of kidney cancer. CircPSD3, circRAPGEF5, circUBAP2, and circTLK1 affect the cell metastasis and EMT of kidney cancer cells by regulating the expression of miRNAs and related proteins. (C) CircRNAs are involved in the apoptosis of kidney cancer. Circ0054537, circ001842, circEGLN3, and circNUP98 affect the cell apoptosis of kidney cancer cells by regulating the expression of miRNAs and related proteins. (D) CircRNAs are involved in the cell metabolism of kidney cancer. Circ0035483, circFOXP1, and circ0054537 affect the cell metabolism of kidney cancer cells by regulating the expression of miRNAs and related proteins