Table 4 Comparison of emerging model for ecosystem research
From: The tumor ecosystem in head and neck squamous cell carcinoma and advances in ecotherapy
Model type | Degree of visualization | Cost | Assay duration | Number of cells per experiment | Drug screening throughput |
|---|---|---|---|---|---|
Mouse PDX | Medium | High | Weeks to months | 105-106 | Low |
GEMM | Low | High | Months | - | Low |
Zebrafish PDX | High | Low | 2–7 days | 102-103 | High |
Organoid | High | Medium | Weeks to months | 102-103 | Very high |