Skip to main content
Fig. 3 | Molecular Cancer

Fig. 3

From: The evolution and heterogeneity of neutrophils in cancers: origins, subsets, functions, orchestrations and clinical applications

Fig. 3

The multiple tumor-related inflammation pathways of TANs driving angiogenesis. TANs not only promote angiogenesis through angiopoietin, but also up-regulate the expression of Bv8, IL-8, and S100A8/A9 [104, 106, 107]. The secretion of MMP9 by TANs, in conjunction with a high NGAL expression in tumor cells, can confer a protective effect and promote angiogenesis via extracellular matrix (ECM) degeneration [98, 99]

Back to article page

Molecular Cancer

ISSN: 1476-4598