Fig. 2
From: ELF5 drives angiogenesis suppression though stabilizing WDTC1 in renal cell carcinoma
High ELF5 expression inhibits RCC cell proliferation, migration, and invasion. (A) RT-qPCR and western blot outcomes of ELF5 expression in30 paired RCC tissues (T) and adjacent normal tissues (N). (B) IHC staining assay was utilized for detecting the staining intensity of ELF5 in RCC tissues. (C) RT-qPCR and western blot outcomes of ELF5 levels in HK-2, 769-P, and A498 cells. (D) Western blot outcomes of the expression of ELF5. (E-F) Colony formation and CCK-8 assays were implemented for detecting proliferative capability when ELF5 / ELF5-ΔSET was overexpressed in cells. (G-H) Transwell assay was carried out for testing cell migratory and invasive capabilities. Two-tailed Student’s t test was performed. The error bars represent SD. **p < 0.01, and ***p < 0.001