Fig. 7
From: Exploring the promising potential of induced pluripotent stem cells in cancer research and therapy
1 The progression of stem cell development, focusing on various aspects. In panel a, it depicts the morphological transformations that occur at different stages of stem cell development. Panel b highlights the molecular processes involved in the acquisition of cellular diversity. Panel c showcases the pluripotent nature of stem cells obtained at different developmental phases. Lastly, panel d provides an overview of the molecular characteristics observed throughout the course of stem cell development. 2 The control of different characteristics in pluripotent stem cells through epitranscriptomic modifications. The regulatory effects of m6A (indicated in red), m1A (in yellow), pseudouridine (in green), and m5C (in blue) modifications are linked to specific biological traits exhibited by pluripotent stem cells. Reprinted from [106] with permission from the Springer Nature