Fig. 2From: A liquid biopsy signature of circulating extracellular vesicles-derived RNAs predicts response to first line chemotherapy in patients with metastatic colorectal cancerPredictive ability of the 22-gene signature in different cohort. The ROC analyses illustrated the predictive ability of this 22-gene model to identify responders in the training set (A), internal validation set (B), and external validation set (C); The scores of enrolled patients in different cohorts which were calculated based on the 22-gene signature: the training cohort (D), the internal validation cohort (E), the external validation cohort (F), the cohort combined chemotherapy with anti-EGFR (G), the cohort combined chemotherapy with anti-VEGF (H). Patients with lower risk score would more likely obtain tumor remission in training group (I), internal validation group (J) and external validation group (K)Back to article page