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Fig. 4 | Molecular Cancer

Fig. 4

From: A bedside to bench study of anti-PD-1, anti-CD40, and anti-CSF1R indicates that more is not necessarily better

Fig. 4

Higher dose of anti-CSF1R increases tumor growth and decreases survival in YUMMER1.7 melanoma model. A. Tumor volumes in untreated YUMMER1.7 melanoma mice or YUMMER1.7 melanoma mice treated with anti-PD-1 + anti-CD40 with either low (200ug) or high (400ug) dose of anti-CSF1R. B. Survival curve of untreated YUMMER1.7 melanoma mice and YUMMER1.7 melanoma mice treated with anti-PD-1 + anti-CD40 with either low (200ug) or high (400ug) dose of anti-CSF1R * p =  < 0.05, **** p =  < 0.0001

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