Table 10 Representative clinical trials of CAR-NKT therapies
Clinical trials | Agents | Cancer types | Phase | Status |
|---|---|---|---|---|
NCT03294954 | Anti-GD2 CAR and IL-15 expressing NKTs | Neuroblastoma | 1 | Active, not recruiting |
NCT03774654 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
NCT05487651 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
NCT04814004 | Anti-CD19 CAR and IL-15 expressing NKTs | B cell malignancies | 1 | Recruiting |
NCT02439788 | Anti-GD2 CAR expressing NKTs | Neuroblastoma | 1 | Withdrawn |