Molecular Cancer

Table 1 Relationships between hsa_circ_0007919 expression and the clinicopathological characteristics of PDAC patients

From: hsa_circ_0007919 induces LIG1 transcription by binding to FOXA1/TET1 to enhance the DNA damage response and promote gemcitabine resistance in pancreatic ductal adenocarcinoma

Clinicopathological	Cases	hsa_circ_0007919 level
parameters	80	High(40)	Low(40)	χ²	p-value
Age^a				0.220	0.639
< 60	28	13	15
≥ 60	52	27	25
Gender^a				0.549	0.459
Female	23	13	10
Male	57	27	30
Tumor location^a				0.879	0.348
Head	52	28	24
Body and tail	28	12	16
Vascular invasion^a				4.588	0.032*
Yes	62	35	27
No	18	5	13
Nerve invasion^a				4.267	0.039*
Yes	60	34	26
No	20	6	14
Degree of differentiation^b				2.453	0.313
Highly	2	0	2
Moderately	27	12	15
Poorly	51	28	23
T stage^b				9.895	0.018*
T1	9	1	8
T2	33	14	19
T3	20	13	7
T4	18	12	6
Lymph node metastasis^b				7.296	0.034*
N0	36	12	24
N1	34	22	12
N2	10	6	4
TNM stage^a				11.958	0.003**
I	24	5	19
II	32	19	13
III	24	16	8

^a Pearson chi-square test; ^b Fisher’s exact test. *P < 0.05, **P < 0.01
TNM staging is classified according to the 8th edition of the American Joint Committee on Cancer (AJCC).

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ISSN: 1476-4598

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