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Fig. 1 | Molecular Cancer

Fig. 1

From: Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors

Fig. 1

MMP expression and its clinical relevance in TNBC. a. Gene expression of MMP genes located on MMP region (chr11q22.2) comparing normal (N = 99) and TNBC (N = 90) patient-derived samples from TCGA consortium. Mann-Whitney test. ns: no significant, *P < 0.05, **P < 0.01. b. Correlation matrix for the expression genes located at the MMP locus located genes (P < 0.01). c. Gene distribution at MMP region (top). Genes were classified according to their location as 5’ or 3’. Gene location was used to define MMP signatures to perform Kaplan-Meier curves of relapse-free survival (left) and overall survival (right)

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Molecular Cancer

ISSN: 1476-4598