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Fig. 2 | Molecular Cancer

Fig. 2

From: Pan-cancer characterization of cell-free immune-related miRNA identified as a robust biomarker for cancer diagnosis

Fig. 2

The diagnostic utility of cell-free immune-related miRNAs (cf-IRmiRNA) signature in detecting cancers. a-d. Receiver operating characteristic curve (ROC), PR curve, and confusion matrix for cf-IRmiRNA signature for cancer diagnosis in the train, validation, test, and external test set. e. t-SNE analysis of the samples from the whole cohort. f. The diagnostic index of cf-IRmiRNAs signature in participants. g. Scatter plot showing the sensitivity and specificity of the diagnostic index in 13 types of cancer. Size indicates the value of Youden index. h. Summary of AUC, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the cf-IRmiRNAs signature in distinguishing each cancer type from non-cancer controls. i. Summary of the early diagnostic utility of the identified signature among each cancer type from non-cancer controls

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Molecular Cancer

ISSN: 1476-4598