Table 1 BCL3 is linked to multiple tumour types. A summary of the publications demonstrating that BCL3 expression is elevated in tumour versus normal tissue and/or correlation between BCL3 expression and poor prognosis (overall survival or metastasis free survival), listed by tumour type
From: Multifaceted roles for BCL3 in cancer: a proto-oncogene comes of age
Tumour type | Elevated expression cancer vs normal | Prognostic Biomarker |
|---|---|---|
Nasopharyngeal/oral | Andrews, 2000 [69] Thornburg, 2003 [70] Mishra, 2006 [71] Chung, 2013 [72] | Â |
Non-Hodgkin Lymphomas | Canoz, 2004 [62] | Â |
Hodgkin Lymphomas | Rassidakis, 2003 [73] Canoz, 2004 [62] | Â |
AML | Â | Niu, 2019 [74] |
Myeloma | Brenne, 2009 [75] | Brenne, 2009 [75] |
Breast | Pratt, 2003 [76] Huo, 2018 [40] Chen, 2016 [14] Schulten, 2017 [77] | Huo, 2018 [40] Chen 2016 [14] Czapiewski, 2022 [78] |
Endometrial | Pallares, 2004 [79] | Â |
Hepatocellular | O’Neil, 2007 [80] Tu, 2016 [81] | Tu, 2016 [81] |
Melanoma | Uffort, 2009 [82] | Diaz-Ramon, 2023 [83] |
Ovarian | Zou, 2018 [84] | Â |
Prostate | Ahlqvist, 2013 [85] | Â |
Renal cell carcinoma | de Souza Braga, 2014 [86] Dai, 2016 [87] | Â |
Colorectal | Saamarthy 2015 [88] Tao, 2018 [89] | Tao, 2018 [89] Zhang, 2020 [90] |
Cervical | Zhao, 2016 [45] | Zhao 2016 [45] |
Gioblastoma | Wu,2016 [15] Fan, 2022 [91] | Wu, 2016 [15] Wu, 2018 [92] Fan, 2022 [91] |
Oesophageal | Puccio, 2018 [93] Soares-Lima, 2021 [94] | Â |
SC- Lung carcinoma | Dimitrakopoulos, 2015 [95] | Â |
NSC – lung carcinoma |  | Dimitrakopoulos, 2019 [96] |
Thyroid | Â | Xiao, 2022 [97] |