JAK/STAT in leukemia: a clinical update

Table 1 JAK2 fusion gene in leukemia

Disease Category	Fusion	Specific Disease	Reference
Myeloproliferative disorder	TEL-JAK2	aCML	[51]
	PCM1-JAK2	aCML	[52]
	PCM1-JAK2	aCML	[53]
	BCR-JAK2	aCML	[54]
Acute Leukemia	PCM1-JAK2	AML	[55]
	TEL-JAK2	ALL	[56]
	PCM1-JAK2	TPALL	[57]
	ETV6-JAK2	ALL	[29]
Chronic Leukemia	ETV6-JAK2	CML	[58]

aCML, atypical chronic myeloid leukemia; TPALL, T-cell precursor ALL PCM1-JAK2: Pericentriolar Material 1-Janus Kinase 2 ETV6-JAK2: also known as TEL-JAK2

ISSN: 1476-4598