Table 1 Mechanism-based classification of SEV inhibitors

Sphingomyelinase inhibitors

GW4869

Cambinol

Spiroepoxide

Imipramine

DPTIP

Manumycin A

ABC transporter inhibitors

Glyburide

Indomethacin

Phosphatidylserine translocation inhibitors

D-pantethine

Bisindolylmaleimide-l

Endosomal membrane inhibitors

Simvastatin

Cytoskeleton-related protein inhibitors

Calpeptin

Chloramidine (Cl-amidine)

NSC23766

Y27632

Cytochalasin D

Protein kinase inhibitors

Y27632

U0126

Imatinib

Dasatinib

ESCRT-pathway inhibitors

Manumycin A

Tipifarnib

Sulphisoxazole

Apatinib

EV release inhibitors

Cannabidiol

SMR peptides

Ketotifen

Dimethyl amiloride

Endocytosis inhibitors

Dynasore

Ikarugamycin

Genistein

Chlorpromazine

MβCD

Heparin

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