Table 2 TDSEV-derived components as prospective biomarkers for the diagnosis and prognosis of different types of cancer
S. No | Types of cancer | SEV components | Diagnostic/Prognostic significance | References |
|---|---|---|---|---|
1 | Breast cancer | miR-223-3p | Biomarker for early detection of breast metastasis | [258] |
2 | Breast cancer | miR-222 | It is connected to lymphatic metastasis in highly expressed breast cancer | [241] |
3 | Lung cancer | miR-106b | It is extensively expressed in serum and has been linked to lymph node metastasis as well as MMP protein expiration in lung cancer metastasis | [259] |
4 | Lung cancer | miR-451a | It aids in the spread of lung cancer to lymph nodes | [240] |
5 | Colon cancer | CD147 | It is substantially expressed in patients with colon cancer | [260] |
6 | Colon cancer | miR-203 | It is significantly expressed in colon cancer and is linked to liver metastasis | [261] |
7 | Prostate cancer | miR-501-3p | It is reduced in prostate tumors, yet it lowers E-cadherin expression and boosts metastasis | [262] |
8 | Prostate cancer | miR-1290 and miR-375 | These are significantly expressed in prostate cancer and are linked to poor overall survival in castration-resistant patients | [263] |
9 | Liver cancer | circRNA- 100,338 | It promotes the metastasis of liver cancer | [264] |
10 | Liver cancer | miR-126 | It is a useful prognostic biomarker for liver cancer | [265] |