Fig. 2From: Selective autophagy in cancer: mechanisms, therapeutic implications, and future perspectivesParkin-independent pathway of mitophagy. The OMM contains a variety of proteins, including BNIP3, BNIP3L, FUNDC1, BCL2L13, FKBP8 and PHB2 as well as other autophagy receptors with LIR motifs that are not subject to ubiquitination. Direct binding of lipidized LC3 and GABARAP family members on the phagosome membrane initiates mitophagyBack to article page