Fig. 8

circRPPH1 promotes TNBC onset and progression in vivo. a The specified tumor cells were injected subcutaneously into nude mice, and xenograft tumors were collected 28 days later. b and c Tumor volumes were measured and counted weekly. d and e Bioluminescence imaging and quantification of lung metastases after tumor cells were injected into the tail vein of nude mice. f and g Representative images of lung metastases in mice and quantification of H&E staining (scale bar, 200 μm). h Schematic illustration of circRPPH1's cancer-promoting mechanisms in TNBC cells