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Fig. 2 | Molecular Cancer

Fig. 2

From: CircPCNXL2 promotes tumor growth and metastasis by interacting with STRAP to regulate ERK signaling in intrahepatic cholangiocarcinoma

Fig. 2

CircPCNXL2 promotes the proliferation and migration of ICC in vitro. (a-b) The efficiency of circPCNXL2 siRNAs or circPCNXL2 plasmid was certified by qRT-PCR. (c) CCK8 assay was performed in HuCCT1 and RBE cells transfected with circPCNXL2 siRNAs or circPCNXL2 plasmid. (d) EdU assay was conducted to evaluate the proliferation in HuCCT1 and RBE cells, scale bar = 50 μm. (e-f) Colony formation assay of HuCCT1 and RBE cells. (g-h) Transwall assay was performed in HuCCT1 and RBE cells transfected with circPCNXL2 siRNAs or circPCNXL2 plasmid, scale bar = 100 μm. (i-j) Wound healing assay was used to evaluate the migration in HuCCT1 and RBE cells, scale bar = 100 μm. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598