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Fig. 3 | Molecular Cancer

Fig. 3

From: CircPCNXL2 promotes tumor growth and metastasis by interacting with STRAP to regulate ERK signaling in intrahepatic cholangiocarcinoma

Fig. 3

CircPCNXL2 facilitates the tumor growth and metastasis of ICC in vivo (a-b) Representative images of subcutaneous xenograft tumors (n = 6) (c-f) Weight and Volume of subcutaneous xenograft tumors show the effect of circPCNXL2 knockdown or overexpression on the formation of ICC. (g-h) Ki-67 staining of subcutaneous xenograft tumors, scale bar = 50 μm. (i-j) Representative images of liver metastasis model in mice inoculated with circPCNXL2 knockdown or overexpression ICC cells. (k) HE staining of liver metastasis model, scale bar = 200 μm. *P < 0.05, **P < 0.01, ***P < 0.001

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Molecular Cancer

ISSN: 1476-4598