Table 1 Clinicopathological parameters of NSCLC patients and correlation with circNOX4 expression (n = 84)
Clinicopathological parameter | N of cases | circNOX4 expression | P value | |
|---|---|---|---|---|
Low | High | |||
Age at diagnosis | ||||
 < 60 | 32 | 11 | 21 | 0.218 |
 ≥ 60 | 52 | 25 | 27 |  |
Sex | ||||
 Male | 66 | 31 | 35 | 0.145 |
 Female | 18 | 5 | 13 |  |
Smoking history | ||||
 Yes | 55 | 24 | 31 | 0.842 |
 No | 29 | 12 | 17 |  |
Histological type | ||||
 Adenocacinoma | 42 | 17 | 25 | 0.806 |
 Squamous cell carcinoma | 34 | 16 | 18 |  |
 Others | 8 | 3 | 5 |  |
Distant metastasis | ||||
 Yes | 54 | 16 | 38 | 0.001** |
 No | 30 | 20 | 10 |  |
LNM | ||||
 Yes | 59 | 25 | 34 | 0.890 |
 No | 25 | 11 | 14 |  |
ECOG PS | ||||
 ≤ 1 | 76 | 32 | 44 | 0.720 |
 2 | 8 | 4 | 4 |  |