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Fig. 2 | Molecular Cancer

Fig. 2

From: Exosome circATP8A1 induces macrophage M2 polarization by regulating the miR-1-3p/STAT6 axis to promote gastric cancer progression

Fig. 2

CircATP8A1 knockdown reduces proliferation and migration in AGS cells. A The relative expression levels of circATP8A1 and linear ATP8A1 after circATP8A1 knockout in AGS cells were detected by qRT-PCR. B The proliferative ability of AGS cells after circATP8A1 knockdown was detected by CCK8 assay. C & D Representative images of clone formation and statistics of colony counts in AGS cells with circATP8A1 knockdown. E & F Microscopic images and quantification of the migration and invasion of AGS cells as described above. P value is determined by t-test for A, B, D, and F. *** P < 0.001. shNC, the knockdown-control group; sh1-circATP8A1 and sh2-circATP8A1, circATP8A1 knockdown group1 and group2

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Molecular Cancer

ISSN: 1476-4598