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Fig. 1 | Molecular Cancer

Fig. 1

From: Bladder-cancer-derived exosomal circRNA_0013936 promotes suppressive immunity by up-regulating fatty acid transporter protein 2 and down-regulating receptor-interacting protein kinase 3 in PMN-MDSCs

Fig. 1

PMN-MDSCs infiltrating the tumor microenvironment with overexpression of FATP2 and low expression of RIPK3. (A) Detection of PMN-MDSCs (CD11b+LOX-1+) (yellow) in bladder cancer tissues and controls (adjacent tissues) by immunofluorescence (bar = 200 μm). (B and C) Immunohistochemical detection of RIPK3 and FATP2 in bladder cancer tissues and adjacent tissues (bar = 200 μm). (D and E) Correlation analysis of expression of RIPK3 or FATP2 and PMN-MDSCs infiltration in bladder tumor tissue. (F) Immunohistochemical detection of LOX-1, RIPK3 and FATP2 expression in human bladder cancer tissues (n = 18). (G) The expression of RIPK3 and FATP2 in bladder cancer patients with different clinical stages. (* P < 0.05)

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Molecular Cancer

ISSN: 1476-4598