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Table 1 Baseline clinical characteristics

From: An international phase II trial and immune profiling of SBRT and atezolizumab in advanced pretreated colorectal cancer

Variable

 

Total

N

%

Age at inclusion (years)

Median (range)

59 (20–81)

 

Gender

Male

38

63

Female

22

37

ECOG PS

0

28

47

1

32

53

T stage

T2

3

6

T3

24

45

T4a

16

30

T4b

6

11

Tx

4

8

N stage

N0

11

21

N1

17

33

N2a

15

29

N2b

4

8

Nx

5

10

Metastatic sitesb

Liver

46

77

Lung

45

52

Peritoneal cavity

14

23

Others

10

17

Number of metastatic sites

1

10

17

2

27

45

3

16

27

 > 3

7

17

Prior treatments

Surgery

49

82

Radiotherapy

19

68

Chemotherapy + TT

58

97

Median N lines (range)

2 (1–5)

 

Molecular status

PDL1 ≥ 1%

11

18

MSS NA

19

32

pMMR

33

55

MSI-H

8a

13

KRAS/NRAS

25

42

HER2

3

5

MET

1

2

PI3KCA

1

2

BRAF

6

10

Atezolizumab

median N cycles (range)

4 (1–94)

 

SBRT (Gy)

Median dose (range)

45 (21–45)

 

Irradiated sites

Lung

30

56

Liver

18

33

Others

8

13

  1. aOne did not receive atezolizumab
  2. bPatients had several metastatic sites so sum of percentages is above 100