Fig. 2From: CTLs heterogeneity and plasticity: implications for cancer immunotherapyDifferentiation trajectories of CD4+ CTLs. These mainly include I) dependence on TCR signaling as the initiating event pathway, (II) signaling through the receptor CRTAM as the initiating event pathway and (III) the epigenetic regulatory modification pathway. This figure was created based on the tools provided by Biorender.com (accessed on 13/10/2023)Back to article page