Fig. 1From: The senescence journey in cancer immunoeditingSenescence inducers and paracrine effects of SnCsOverview of senescence inducers and paracrine effects of SnCs on the surrounding microenvironment. The senescence program can be activated by different stress stimuli (shown on the left) such as cytotoxic chemotherapeutic drugs, replicative and oxidative stress. On the other hand, SASP factors produce paracrine effects impinging on cancer onset and progression (shown on the right). SASP can induce senescence of surrounding cells (paracrine senescence), facilitate tissue remodeling and recruitment of immune cellsCreated with BioRender.com with granted permission and licenseBack to article page