Skip to main content
Fig. 1 | Molecular Cancer

Fig. 1

From: Clinical effectiveness of a multitarget urine DNA test for urothelial carcinoma detection: a double-blinded, multicenter, prospective trial

Fig. 1

Flow diagram of algorithm development and clinical validation of the mt-utDNA test. A total of 1,329 participants were enrolled in this study. The algorithm development cohort included 382 individuals involved in the construction of the integrated prediction model and the determination of appropriate clinical cutoffs of the mt-utDNA test. The performance of the test was validated in the prospective validation cohort (n = 947) for UC detection according to the clinical diagnosis results. Sanger sequencing and postsurgical follow-up were performed to verify the results of the test. UC: urothelial carcinoma; mt-utDNA test: multitarget urine tumor DNA test

Back to article page

Molecular Cancer

ISSN: 1476-4598