Fig. 5
From: Crosstalk between metabolism and cell death in tumorigenesis
The expression levels of cuproptosis genes in colorectal cancer and hepatocellular carcinoma. (A and B) The expression levels of cuproptosis genes in colorectal cancer (A) and hepatocellular carcinoma (B). The blue dot represents the genes that are down-regulated in cancer, the red dot means these genes are up-regulated in cancer (p < 0.05), and those with no significant difference compared with normal tissues are indicated in gray. Both mRNA Seq data and clinical data collected from TCGA database, including COAD, READ and LIHC reveal that the COAD and READ are merged into colorectal cancer based on gene names. In the mRNA differential expression analysis, the R package Deseq2 was used to differential expression analysis. The genes with a fold change (FC) > 0 and an adjusted P-value (FDR) > 0.05 were retained for further analysis