Skip to main content

Table 2 Selected drugs or molecules associated with necrosis in oncology research, the effects on necrosis and targets of action

From: Crosstalk between metabolism and cell death in tumorigenesis

Cell death

Medicine

Inhibition or promotion

Target

References

Necrosis

Tetrathiomolybdate

Promotion

Inhibit angiogenesis

[281]

 

Necrosis

Simvastatin,

Metformin

Promotion

Ripk1, Ripk3

[282]

 

Necrosis

Melatonin

Promotion

Bcl2/Bax

[283]

 

Necrosis

CuZnSOD, MnSOD

Inhibition

Inhibit ROS generate

[284]

Â