Crosstalk between metabolism and cell death in tumorigenesis

Table 3 Selected drugs or molecules associated with necroptosis in oncology research, their effects on necroptosis and targets of action

Cell death	Medicine	Inhibition or promotion	Target	References
Necroptosis	NO.0449 − 0145	Promotion	APE1	[275]
Necroptosis	CBL0137	Promotion	ZBP1	[86]
Necroptosis	BV6	Promotion	TNF-α	[285]
Necroptosis	Shikonin	Promotion	PKM2	[286]
Necroptosis	Necrostatin-1	Inhibition	RIP1	[287]
Necroptosis	NBC1	Inhibition	Hsp70	[288]

ISSN: 1476-4598