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Table 6 Selected drugs or molecules associated with autophagy in oncology research, their effects on autophagy and targets of action

From: Crosstalk between metabolism and cell death in tumorigenesis

Cell death

Medicine

Inhibition or promotion

Target

References

Autophagy

Carfilzomib, ONX 0912

Promotion

ATF4

[315]

 

Autophagy

Dihydromyricetin

Promotion

ROS/STAT3

[316]

 

Autophagy

Rapamycin, Latcripin-7 A, Metformin, RAD001

Promotion

mTOR

[317,318,319,320]

 

Autophagy

Narciclasine

Promotion

AMPK/ULK1

[321]

 

Autophagy

PX-866

Inhibition

PI3K

[322]

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