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Fig. 9 | Molecular Cancer

Fig. 9

From: Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation

Fig. 9

SERPINE1 expression was elevated in tumors after NAT and predicted poor prognosis in cohort 1. (A) IHC staining of SERPINE1 in matched LARC tissues. (B) The IRS of SERPINE1 in matched LARC tissues. (C) OS of CRC patients from the TCGA database. (D) OS and (E) RFS of colon patients from the Kaplan-Meier plotter database. (F) DFS of 22 LARC patients in cohort 1. The plot was generated according to the difference between pre-NAT IRS and post-NAT IRS of SERPINE1 (SERPINE1-diff). *p < 0.05, **p < 0.01, and ***p < 0.001

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Molecular Cancer

ISSN: 1476-4598