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Table 1 p16 and p21 expression in LARC tissues (cohort 1)

From: Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation

Factors

pre-NAT (n = 22)

post-NAT (n = 22)

χ2

p value

p16 positive

7 (31.82%)

21 (95.45%)

16.60

<0.001

p16 negative

15 (68.18%)

1 (4.55%)

  

p21 positive

7 (31.82%)

18 (81.82%)

9.26

0.002

p21 negative

15 (68.18%)

4 (18.18%)

  
  1. Data were analyzed by χ2 test with Yate’s correction