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Table 2 p16 and p21 expression in mCRC tissues (cohort 2)

From: Therapy-induced senescent tumor cell-derived extracellular vesicles promote colorectal cancer progression through SERPINE1-mediated NF-κB p65 nuclear translocation

Factors

pre-Treat (n = 30)

post-Treat (n = 30)

χ2

p value

p16 positive

7 (23.33%)

17 (56.67%)

6.94

0.008

p16 negative

23 (76.67%)

13 (43.33%)

  

p21 positive

16 (53.33%)

24 (80.00%)

4.80

0.029

p21 negative

14 (46.67%)

6 (20.00%)

  
  1. Data were analyzed by Pearson’s χ2 test