Fig. 4
From: Functional CRISPR screens in T cells reveal new opportunities for cancer immunotherapies
Summarisation of CRISPR screen results according to stages of T cell life cycle. CRISPR screens have successfully identified crucial regulatory factors and networks central to T cell immunity in the context of cancer treatment. High-throughput CRISPR screens were conducted to identify genes that govern various aspects of T cell function including activation, proliferation, differentiation, effector function, and exhaustion. Positive regulators are indicated in red, whereas negative regulators are represented in green