Figure 2

Illustration of LOH of tumors representing minimal deletions at 5p15.3 (T-6) (left panel) and 5p15.3-15.2 (T-59) (right panel). The STRP markers are shown above and the tumor numbers below of each panel. N, normal; T, tumor; Asterisks indicate LOH. Reduction of signal intensity by 50% or more of one of the alleles in tumor DNA compared with the intensity of constitutional alleles was considered LOH.