Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

New Content Item © © DeAngelis / science photo library

This series of review articles aims to highlight significant findings and advances in our understanding of the role of the TME in cancer biology. The tumor microenvironment (TME) has an effect on tumor development, growth, and resistance to therapy. Continuous interactions and exchanges between tumor cells and the TME are involved in angiogenesis, tumor genetic diversity, immune escape, and metastasis. - Read more

Featured Article: Role of the NLRP3 inflammasome in cancer

In this review, Sahebkar et al. summarize the current knowledge on the contribution of the NLRP3 inflammasome on potential cancer promotion and therapy.

Thematic Series Published in 2018

Series of Review Articles: Oncogenic Signaling of Tyrosine Kinase in Cancer: Challenges and Therapeutic Opportunities

Content type: Research
| 18 April 2019

Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

Authors: Shouping Xu, Peiyuan Wang, Jian Zhang, Hao Wu, Shiyao Sui, Jinfeng Zhang, Qin Wang, Kun Qiao, Weiwei Yang, Hongbiao Xu and Da Pang
Content type: Research
| 13 April 2019

Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation

Authors: Lisha Ai, Shidai Mu, Chunyan Sun, Fengjuan Fan, Han Yan, You Qin, Guohui Cui, Yadan Wang, Tao Guo, Heng Mei, Huafang Wang and Yu Hu
Content type: Research
| 13 April 2019

m⁶A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1

Authors: Yingmin Wu, Xiangling Yang, Zhuojia Chen, Lin Tian, Guanmin Jiang, Feng Chen, Jiexin Li, Panpan An, Linlin Lu, Nan Luo, Jun Du, Hong Shan, Huanliang Liu and Hongsheng Wang
Content type: Research
| 11 April 2019

CD103-positive CSC exosome promotes EMT of clear cell renal cell carcinoma: role of remote MiR-19b-3p

Authors: Lu Wang, Guang Yang, Danfeng Zhao, Jiaqi Wang, Yang Bai, Qiang Peng, Hongzhi Wang, Ruizhe Fang, Guang Chen, Zhichao Wang, Keliang Wang, Guangbin Li, Yinhui Yang, Ziqi Wang, Pengyu Guo, Li Peng…
Content type: Research
| 10 April 2019

Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy

Authors: Ke Xu, Dongkyoo Park, Andrew T. Magis, Jun Zhang, Wei Zhou, Gabriel L. Sica, Suresh S. Ramalingam, Walter J. Curran and Xingming Deng

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Content type: Research
| 28 September 2014

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

Authors: Ruochuan Sun, Jifeng Wu, Yuanyuan Chen, Mingdian Lu, Shangxin Zhang, Daru Lu and Yongxiang Li
Content type: Review
| 2 August 2013

The complexity of NF-κB signaling in inflammation and cancer

Authors: Bastian Hoesel and Johannes A Schmid
Content type: Research
| 9 October 2014

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Authors: Donatella Del Bufalo, Marianna Desideri, Teresa De Luca, Marta Di Martile, Chiara Gabellini, Valentina Monica, Simone Busso, Adriana Eramo, Ruggero De Maria, Michele Milella and Daniela Trisciuoglio
Content type: Research
| 22 July 2010

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

Authors: María M Caffarel, Clara Andradas, Emilia Mira, Eduardo Pérez-Gómez, Camilla Cerutti, Gema Moreno-Bueno, Juana M Flores, Isabel García-Real, José Palacios, Santos Mañes, Manuel Guzmán and Cristina Sánchez
Content type: Review
| 29 May 2014

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Authors: Mildred Felder, Arvinder Kapur, Jesus Gonzalez-Bosquet, Sachi Horibata, Joseph Heintz, Ralph Albrecht, Lucas Fass, Justanjyot Kaur, Kevin Hu, Hadi Shojaei, Rebecca J Whelan and Manish S Patankar

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Editor-in-Chief

Christophe Nicot, Kansas University Medical Center, USA

Aims and scope

Molecular Cancer is an open access, peer-reviewed journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science.

Impact Factor

Molecular Cancer has an Impact Factor of 7.776 and is ranked in the top 10% of both its JCR Categories.

It is currently ranked at 27 out of 292 (Q1) in the Biochemistry and Molecular Biology category and 22 out of 222 (Q1) in the Oncology category of Journal Citation Reports.

Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

Featured Article: Role of the NLRP3 inflammasome in cancer

Thematic Series Published in 2018

Articles

Ai-lncRNA EGOT enhancing autophagy sensitizes paclitaxel cytotoxicity via upregulation of ITPR1 expression by RNA-RNA and RNA-protein interactions in human cancer

Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation

m⁶A-induced lncRNA RP11 triggers the dissemination of colorectal cancer cells via upregulation of Zeb1

CD103-positive CSC exosome promotes EMT of clear cell renal cell carcinoma: role of remote MiR-19b-3p

Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

The complexity of NF-κB signaling in inflammation and cancer

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Editor-in-Chief

Aims and scope

Impact Factor

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Annual Journal Metrics

Molecular Cancer

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