Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

New Content Item © © DeAngelis / science photo library

This series of review articles aims to highlight significant findings and advances in our understanding of the role of the TME in cancer biology. The tumor microenvironment (TME) has an effect on tumor development, growth, and resistance to therapy. Continuous interactions and exchanges between tumor cells and the TME are involved in angiogenesis, tumor genetic diversity, immune escape, and metastasis. - Read more

Featured Article: Role of the NLRP3 inflammasome in cancer

In this review, Sahebkar et al. summarize the current knowledge on the contribution of the NLRP3 inflammasome on potential cancer promotion and therapy.

Thematic Series Published in 2018

Series of Review Articles: Oncogenic Signaling of Tyrosine Kinase in Cancer: Challenges and Therapeutic Opportunities

Content type: Research
| 24 June 2019

METTL3 facilitates tumor progression via an m⁶A-IGF2BP2-dependent mechanism in colorectal carcinoma

Authors: Ting Li, Pei-Shan Hu, Zhixiang Zuo, Jin-Fei Lin, Xingyang Li, Qi-Nian Wu, Zhan-Hong Chen, Zhao-Lei Zeng, Feng Wang, Jian Zheng, Demeng Chen, Bo Li, Tie-Bang Kang, Dan Xie, Dongxin Lin, Huai-Qiang Ju…
Content type: Research
| 22 June 2019

Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN

Authors: Qun Lu, Tianyao Liu, Huijin Feng, Rong Yang, Xiaozhi Zhao, Wei Chen, Bo Jiang, Haixiang Qin, Xu Guo, Minghui Liu, Limin Li and Hongqian Guo
Content type: Research
| 22 June 2019

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

Authors: Jie Han, Jing-zi Wang, Xiao Yang, Hao Yu, Rui Zhou, Hong-Cheng Lu, Wen-Bo Yuan, Jian-chen Lu, Zi-jian Zhou, Qiang Lu, Ji-Fu Wei and Haiwei Yang
Content type: Research
| 20 June 2019

A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer

Authors: Peng Gu, Xu Chen, Ruihui Xie, Weibin Xie, Li Huang, Wen Dong, Jinli Han, Xiaodong Liu, Jihong Shen, Jian Huang and Tianxin Lin
Content type: Research
| 20 June 2019

Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity

Authors: Lifeng Li, Li Yang, Shiqi Cheng, Zhirui Fan, Zhibo Shen, Wenhua Xue, Yujia Zheng, Feng Li, Dong Wang, Kai Zhang, Jingyao Lian, Dan Wang, Zijia Zhu, Jie Zhao and Yi Zhang

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Content type: Research
| 28 September 2014

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

Authors: Ruochuan Sun, Jifeng Wu, Yuanyuan Chen, Mingdian Lu, Shangxin Zhang, Daru Lu and Yongxiang Li
Content type: Review
| 2 August 2013

The complexity of NF-κB signaling in inflammation and cancer

Authors: Bastian Hoesel and Johannes A Schmid
Content type: Research
| 9 October 2014

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Authors: Donatella Del Bufalo, Marianna Desideri, Teresa De Luca, Marta Di Martile, Chiara Gabellini, Valentina Monica, Simone Busso, Adriana Eramo, Ruggero De Maria, Michele Milella and Daniela Trisciuoglio
Content type: Research
| 22 July 2010

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

Authors: María M Caffarel, Clara Andradas, Emilia Mira, Eduardo Pérez-Gómez, Camilla Cerutti, Gema Moreno-Bueno, Juana M Flores, Isabel García-Real, José Palacios, Santos Mañes, Manuel Guzmán and Cristina Sánchez
Content type: Review
| 29 May 2014

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Authors: Mildred Felder, Arvinder Kapur, Jesus Gonzalez-Bosquet, Sachi Horibata, Joseph Heintz, Ralph Albrecht, Lucas Fass, Justanjyot Kaur, Kevin Hu, Hadi Shojaei, Rebecca J Whelan and Manish S Patankar

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Editor-in-Chief

Christophe Nicot, Kansas University Medical Center, USA

Aims and scope

Molecular Cancer is an open access, peer-reviewed journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science.

Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

Featured Article: Role of the NLRP3 inflammasome in cancer

Thematic Series Published in 2018

Articles

METTL3 facilitates tumor progression via an m⁶A-IGF2BP2-dependent mechanism in colorectal carcinoma

Circular RNA circSLC8A1 acts as a sponge of miR-130b/miR-494 in suppressing bladder cancer progression via regulating PTEN

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer

Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

The complexity of NF-κB signaling in inflammation and cancer

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Editor-in-Chief

Aims and scope

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Molecular Cancer

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