Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

New Content Item © © DeAngelis / science photo library

This series of review articles aims to highlight significant findings and advances in our understanding of the role of the TME in cancer biology. The tumor microenvironment (TME) has an effect on tumor development, growth, and resistance to therapy. Continuous interactions and exchanges between tumor cells and the TME are involved in angiogenesis, tumor genetic diversity, immune escape, and metastasis. - Read more

Featured Article: Role of the NLRP3 inflammasome in cancer

In this review, Sahebkar et al. summarize the current knowledge on the contribution of the NLRP3 inflammasome on potential cancer promotion and therapy.

Thematic Series Published in 2018

Series of Review Articles: Oncogenic Signaling of Tyrosine Kinase in Cancer: Challenges and Therapeutic Opportunities

Content type: Research
| 20 June 2019

A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer

Authors: Peng Gu, Xu Chen, Ruihui Xie, Weibin Xie, Li Huang, Wen Dong, Jinli Han, Xiaodong Liu, Jihong Shen, Jian Huang and Tianxin Lin
Content type: Research
| 20 June 2019

Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity

Authors: Lifeng Li, Li Yang, Shiqi Cheng, Zhirui Fan, Zhibo Shen, Wenhua Xue, Yujia Zheng, Feng Li, Dong Wang, Kai Zhang, Jingyao Lian, Dan Wang, Zijia Zhu, Jie Zhao and Yi Zhang
Content type: Research
| 10 June 2019

Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes

Authors: Zhenhua Luo, Weixu Wang, Feng Li, Zhou Songyang, Xuyang Feng, Changchang Xin, Zhiming Dai and Yuanyan Xiong
Content type: Research
| 1 June 2019

Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

Authors: Peng-Fei Zhang, Chuan-Yuan Wei, Xiao-Yong Huang, Rui Peng, Xuan Yang, Jia-Cheng Lu, Chi Zhang, Chao Gao, Jia-Bin Cai, Ping-Ting Gao, Dong-Mei Gao, Guo-Ming Shi, Ai-Wu Ke and Jia Fan
Content type: Review
| 29 May 2019

The role of m⁶A RNA methylation in human cancer

Authors: Xiao-Yu Chen, Jing Zhang and Jin-Shui Zhu

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Content type: Research
| 28 September 2014

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

Authors: Ruochuan Sun, Jifeng Wu, Yuanyuan Chen, Mingdian Lu, Shangxin Zhang, Daru Lu and Yongxiang Li
Content type: Review
| 2 August 2013

The complexity of NF-κB signaling in inflammation and cancer

Authors: Bastian Hoesel and Johannes A Schmid
Content type: Research
| 9 October 2014

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Authors: Donatella Del Bufalo, Marianna Desideri, Teresa De Luca, Marta Di Martile, Chiara Gabellini, Valentina Monica, Simone Busso, Adriana Eramo, Ruggero De Maria, Michele Milella and Daniela Trisciuoglio
Content type: Research
| 22 July 2010

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

Authors: María M Caffarel, Clara Andradas, Emilia Mira, Eduardo Pérez-Gómez, Camilla Cerutti, Gema Moreno-Bueno, Juana M Flores, Isabel García-Real, José Palacios, Santos Mañes, Manuel Guzmán and Cristina Sánchez
Content type: Review
| 29 May 2014

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Authors: Mildred Felder, Arvinder Kapur, Jesus Gonzalez-Bosquet, Sachi Horibata, Joseph Heintz, Ralph Albrecht, Lucas Fass, Justanjyot Kaur, Kevin Hu, Hadi Shojaei, Rebecca J Whelan and Manish S Patankar

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Editor-in-Chief

Christophe Nicot, Kansas University Medical Center, USA

Aims and scope

Molecular Cancer is an open access, peer-reviewed journal interested in attracting high-quality original research and reviews that present or highlight significant advances in all areas of cancer and related biomedical science.

Molecular Cancer

Newly Published: Microvesicles and Tumor Microenvironment in Cancer Development and Resistance to Therapies

Featured Article: Role of the NLRP3 inflammasome in cancer

Thematic Series Published in 2018

Articles

A novel AR translational regulator lncRNA LBCS inhibits castration resistance of prostate cancer

Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity

Pan-cancer analysis identifies telomerase-associated signatures and cancer subtypes

Circular RNA circTRIM33–12 acts as the sponge of MicroRNA-191 to suppress hepatocellular carcinoma progression

The role of m⁶A RNA methylation in human cancer

Down regulation of Thrombospondin2 predicts poor prognosis in patients with gastric cancer

The complexity of NF-κB signaling in inflammation and cancer

Histone deacetylase inhibition synergistically enhances pemetrexed cytotoxicity through induction of apoptosis and autophagy in non-small cell lung cancer

Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

Editor-in-Chief

Aims and scope

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Molecular Cancer

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