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Figure 5 | Molecular Cancer

Figure 5

From: Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming

Figure 5

NK cells cultured in reoTCM are activated against melanoma cell targets. (A) NK cells were cultured in the presence of virus-filtered reoTCM/non-reoTCM overnight and CD69 expression determined. (B) NK cells were cultured in the presence of filtered reoTCM or non-reoTCM for 48 hours and then co-cultured with Mel-888 tumour targets prior to CD107 and intracellular IFNγ assessment. Results shown are gated on CD56+ve/CD3-ve cell populations and are representative of 4 independent donors.

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Molecular Cancer

ISSN: 1476-4598