Figure 3From: Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancerThromboxane synthase expression in NSCLC cells and effects of selective inhibition on tumour cell growth. A modest basal expression of TXS was observed in A-549 and SKMES-1 cell lines at both the RNA (A) and protein (B) levels. Selective TXS inhibition resulted in a significant reduction in tumour cell survival in both A-549 (C) and SKMES-1 (D) cell lines. Data is expressed as mean ± SEM, with proliferation values expressed as a percentage of the controls (* p < 0.05 relative to control, # p < 0.05 relative to control; n = 3).Back to article page