Table 3 Functional annotation of predicted targets

Biological process

Regulation of transcription

407

22.0

4.28E-20

Intracellular signaling cascade

208

11.24

5.52E-12

Protein amino acid phosphorylation

127

6.86

2.03E-11

Regulation of RNA metabolic process

269

14.54

5.67E-10

Negative regulation of cellular biosynthetic process

107

5.78

8.68E-10

Phosphate metabolic process

159

8.59

7.5E-9

Regulation of small GTPase mediated signal transduction

58

3.14

1.41E-8

Regulation of Ras protein signal transduction

51

2.8

1.89E-8

Regulation of apoptosis

132

7.1

1.35E-7

Vesicle-mediated transport

101

5.5

2.2E-7

Negative regulation of signal transduction

50

2.7

2.77E-7

Protein transport

124

6.7

5.48E-7

Transmembrane receptor protein tyrosine kinase signaling pathway

49

2.65

1.04E-6

Regulation of cell migration

40

2.16

1.57E-6

Positive regulation of cell differentiation

49

2.65

2.03E-6

Intracellular transport

108

5.84

2.04E-6

Regulation of cell proliferation

124

6.7

2.99E-6

Hematopoietic or lymphoid organ development

52

2.8

7.41E-6

Regulation of protein kinase cascade

47

2.5

9.5E-5

Regulation of protein kinase activity

60

3.24

1.05E-4

Regulation of erythrocyte differentiation

9

0.5

2.41E-4

Regulation of myeloid cell differentiation

19

1.2

2.42E-4

Molecular function

Transcription regulator activity

268

14.5

8.81E-19

GTPase regulator activity

82

4.4

1.32E-8

Protein kinase activity

110

5.95

2.33E-8

Cytoskeletal protein binding

90

4.86

1.06E-6

Transcription repressor activity

63

3.41

1.46E-6

Protein domain specific binding

65

3.51

1.67E-6

DNA binding

314

16.97

2.51E-6

Zinc ion binding

303

16.38

3.7E-5

Chromatin binding

34

1.84

4.03E-5

Cation binding

509

27.51

1.28E-4

SH3 domain binding

24

1.3

1.51E-4

Pathway

Endocytosis

45

2.43

1.93E-8

Pathways in cancer

64

3.46

1.41E-7

mTOR signaling pathway

16

0.86

1.13E-4

Hedgehog signaling pathway

16

0.86

2.82E-4

Chronic myeloid leukemia

19

1.03

3.21E-4

Focal adhesion

37

2.0

3.39E-4

Wnt signaling pathway

29

1.57

8.77E-4