Figure 2
From: RNA polymerase III transcription in cancer: the BRF2 connection
BRF2-TFIIIB is a target of regulation by tumor suppressors and oncogenic products. Depiction of tumor suppressor and oncogenic products involved in the regulation of BRF2-TFIIIB. The tumor suppressors, p53, RB and BRCA1 are depicted as red circles. The oncogenic kinase CK2 is depicted by a green box and functions in regulating BRF2-TFIIIB. The stress related protein Maf1 is depicted by a triangle and functions in inhibiting BRF2-TFIIIB.