Figure 5
From: RNA polymerase III transcription in cancer: the BRF2 connection
Oncomine analysis of BRF2 expression in leukemia and lymphoma. As demonstrated in Figure 3, BRF2 is overexpressed in both leukemia and lymphoma, cancer vs cancer datasets. We further queried the Oncomine database to analyze BRF2 expression in both leukemia and lymphoma. Figure 5A represents an analysis performed across 22 leukemia analyses found within Oncomine. The p-value, 0.028, represents a student's t-test measuring BRF2 overexpression in cancerous tissues, and the red represents significant overexpression. This analysis shows that BRF2 is significantly overexpressed across leukemia. The table states the datasets analyzed and the number of patient samples used in each study. Figure 5B represents an analysis performed across 4 lymphoma analyses found within Oncomine. The p-value, 0.011, represents a student's t-test measuring BRF2 overexpression in cancerous tissue and the red represents significant overexpression. This analysis shows that BRF2 is significantly overexpressed across lymphoma. The table states the datasets used for analysis and the number of patient samples used in each study. (Oncomine database).