Table 1 The frequency of gene promoter methylation of 10 tumor suppressor genes in NPC, high risk and normal subjects.
From: Epigenetic markers for early detection of nasopharyngeal carcinoma in a high risk population
Gene | NPC group (paraffin and/or brushing) | High Risk Group (brushing) | EBV-normal carriers (brushing) |
|---|---|---|---|
CHFR | 31/53 (58.5%) | 0/22 (0.0%) | 0/25 (0.0%) |
RIZ1 | 30/53 (56.6%) | 0/22 (0.0%) | 0/25 (0.0%) |
WIF1 | 30/49 (61.2%) | 4/22 (18.2%) | 0/25 (0.0%) |
p16 | 35/53 (66.0%) | 6/22 (27.2%) | 0/25 (0.0%) |
RASSF2A | 14/48 (29.2%) | 0/22 (0.0%) | 0/25 (0.0%) |
RASSF1A | 40/53 (75.5%) | 0/22 (0.0%) | 1/25 (4.0%) |
DAPK1 | 42/53 (79.2%) | 9/22 (40.9%) | 12/25 (48.0%) |
DLC1 | 40/52 (76.9%) | 9/22 (40.9%) | 16/25 (64.0%) |
CDH13 | 41/53 (77.4%) | 16/22 (72.7) | 16/25 (64.0%) |
CADM1 | 37/53 (69.8%) | 8/22 (36.4%) | 18/25 (72.0%) |