Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer

Table 1 Association between MCM7-positive in NSCLC and characteristics of patients

		Total	MCM7 positive	MCM7 negative	P-value* positive vs negative
		n = 331	n = 196	n = 135
Gender
	Male	236	156	80	<0.0001
	Female	95	40	55
Age(years)
	<65	168	107	61	NS
	≧65	163	89	74
Histological type
	ADC	214	101	113
	SCC	78	63	15	<0.0001^†
	Others**	39	32	7
pT factor
	T1T2	227	127	100	NS
	T3T4	104	69	35
pN factor
	N0	197	99	98	<0.0001
	N1+N2	134	97	37

Abbreviations: ADC, adenocarcinoma; SCC, squamous-cell carcinoma; NS, not siginificant.
*Fisher's exact test.
**Others: large-cell carcinoma (LCC) and adenosquamous-cell carcinoma (ASC).
^†ADC vs non-ADC.

ISSN: 1476-4598