Figure 9From: The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferationDownregualtion of RECQ1 triggers spontaneous RAD51 foci accumulation. A) Western blot analysis of T98G cell lines transiently transfected with a RECQ1-specific siRNA duplex. L indicates the Luciferase siRNA control, R the siRNA against RECQ1. B) The pictures show the immunostaining of endogenous RECQ1 and RAD51 on T98G cells after treatment with anti-RECQ1 siRNA or control siRNAs. C) The graph shows the percentage of cells that contain a defined number of RAD51 foci per cell.Back to article page