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Figure 7 | Molecular Cancer

Figure 7

From: Identification of an epigenetic biomarker panel with high sensitivity and specificity for colorectal cancer and adenomas

Figure 7

Real-time PCR analysis of SNCA in cancer cell lines with known methylation status. A) Gene expression and DNA promoter methylation status of SNCA in cancer cell lines. The quantitative gene expression levels are displayed as ratios between the median of SNCA and the average of two endogenous controls, GUSB and ACTB. *Partially methylated signifies cell lines with the presence of both a methylated and unmethylated band for the MSP analysis, which most likely reflect monoallelic or heterogeneous methylation. B) Relative gene expression of SNCA in six colon cancer cell lines treated with 1 μM of 5-aza-2'deoxycytidine for 72 h (AZA), 0.5 μM of trichostatin A for 12 h (TSA), and a combination of both drugs (AZA+TSA).

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Molecular Cancer

ISSN: 1476-4598