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Table 4 Univariate and multivariate (with and without MBC-based classifier) DFS analyses by Cox regression of basal tumors: public series

From: Kinome expression profiling and prognosis of basal breast cancers

 

Univariate Analysis

 

Multivariate Analysis*

  
 

N

HR [95%CI]

p -value

N

HR [95%CI]

p -value

HR [95%CI]

p -value

Age ≤ 50 ( vs > 50y)

253

0.96 [0.65-1.41]

0.84

     

pT > 20 mm ( vs ≤ 20 mm)

275

1.40 [0.93-2.11]

0.11

     

pN pos ( vs neg)

301

1.53 [1.04-2.25]

0.032

301

1.58 [1.07-2.33]

0.021

1.46 [0.99-2.16]

0.06

Grd 2-3 ( vs 1)

302

3.00 [0.74-12.1]

0.12

     

ER pos ( vs neg)

315

0.68 [0.45-1.03]

0.07

     

Chemotherapy

236

1.28 [0.77-2.14]

0.34

     

Hormone therapy

250

1.01 [0.41-2.48]

0.98

     

MBC-based classifier

380

0.59 [0.43-0.82]

1.72 E-04

301

  

0.59 [0.40-0.87]

7.5 E-03

Immune metagene High ( vs Low)

380

0.45 [0.29-0.69]

2.4 E04

301

2.15 [1.32-3.50]

0.0022

0.54 [0.33-0.89]

0.015

  1. * multavariate analyses were performed without (left) and with (right) the medullary-based classifier.
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Molecular Cancer

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