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Table 4 Univariate and multivariate (with and without MBC-based classifier) DFS analyses by Cox regression of basal tumors: public series

From: Kinome expression profiling and prognosis of basal breast cancers

  Univariate Analysis   Multivariate Analysis*   
  N HR [95%CI] p -value N HR [95%CI] p -value HR [95%CI] p -value
Age ≤ 50 ( vs > 50y) 253 0.96 [0.65-1.41] 0.84      
pT > 20 mm ( vs ≤ 20 mm) 275 1.40 [0.93-2.11] 0.11      
pN pos ( vs neg) 301 1.53 [1.04-2.25] 0.032 301 1.58 [1.07-2.33] 0.021 1.46 [0.99-2.16] 0.06
Grd 2-3 ( vs 1) 302 3.00 [0.74-12.1] 0.12      
ER pos ( vs neg) 315 0.68 [0.45-1.03] 0.07      
Chemotherapy 236 1.28 [0.77-2.14] 0.34      
Hormone therapy 250 1.01 [0.41-2.48] 0.98      
MBC-based classifier 380 0.59 [0.43-0.82] 1.72 E-04 301    0.59 [0.40-0.87] 7.5 E-03
Immune metagene High ( vs Low) 380 0.45 [0.29-0.69] 2.4 E04 301 2.15 [1.32-3.50] 0.0022 0.54 [0.33-0.89] 0.015
  1. * multavariate analyses were performed without (left) and with (right) the medullary-based classifier.