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Figure 2 | Molecular Cancer

Figure 2

From: MicroRNA-194 inhibits epithelial to mesenchymal transition of endometrial cancer cells by targeting oncogene BMI-1

Figure 2

Silencing of BMI-1 expression reverts EMT phenotype and reduces EC cell invasion. A. Comparison of BMI-1 levels in un-transfected HEC-50B-HI, HEC-50B-HI-BMI-1 shRNA and control shRNA cells. B. Morphological changes of HEC-50B-HI cells after knockdown of BMI-1 expression 27 (magnification × 100). C. Effects of BMI-1 suppression on cell invasion ability using Matrigel invasion assay. Data represent the mean ± SE of three independent experiments. *P < 0.01. D. Western blots of epithelial marker E-cadherin and mesenchymal marker Vimentin in un-transfected HEC-50B-HI, HEC-50B-HI-BMI-1 shRNA and control shRNA cells.

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Molecular Cancer

ISSN: 1476-4598