Figure 4

Effect of rhoA and ROCK inhibition on cell growth: Percent growth inhibition in HL60, K562 and BaF3/bcr-abl/T315I treated with - A) PO against rhoA, B) PS against rhoA, for 24 and 48 hours and C) C3 exoenzyme and Y-27632, for 48 hours. * Indicates significantly higher growth inhibition than the respective untreated cells and treated HL-60.